Magnetic Resonance Spectroscopy Examines Heart Failures - January 2005

31 January 2005 - Magnetic Resonance Spectroscopy (MRS) was recently used to measure the rate at which the human heart produces adenosine trisphosphate (ATP) through the creatine kinase reaction.  The study provided direct observation of ATP flux among healthy subjects and those with failing heart, and supports the “energy starvation” hypothesis in heart failure.

The study can be found at: RG Weiss, G Gerstenblith, and PA Bottomley, “ATP flux through creatine kinase in the normal, stressed, and failing human heart,” Proc. National Academy of Science, 18 Jan 2005, 102(3), 808-813.